{"id":18773,"date":"2016-04-29T22:44:48","date_gmt":"2016-04-29T20:44:48","guid":{"rendered":"http:\/\/www.atousante.com\/en\/?p=18773"},"modified":"2018-02-19T08:33:28","modified_gmt":"2018-02-19T06:33:28","slug":"dengue-fever-vaccine-is-now-available-in-3-countries","status":"publish","type":"post","link":"https:\/\/www.atousante.com\/en\/dengue-fever-vaccine-is-now-available-in-3-countries\/","title":{"rendered":"Dengue fever vaccine is now available in 3 countries"},"content":{"rendered":"

Until recently there has been no truly effective prevention against dengue except avoiding getting bit. Sanofi has produced a dengue fever vaccine that is now available in Brazil The Philippines and Mexico but\u00a0it is for use only for people who live in these areas of high endemicity, and not for travellers.<\/p><\/blockquote>\n

The first dengue fever vaccine<\/h2>\n

CYD-TDV is the first dengue vaccine to be licensed :\u00a0a live recombinant tetravalent dengue vaccine developed by Sanofi Pasteur , given as a 3-dose series on a 0\/6\/12 month schedule.<\/span><\/p>\n

Dengue : the disease<\/h2>\n

Dengue is caused by any one of four closely related dengue viruses (DENV). These viruses are related to the viruses that cause West Nile infection and yellow fever.
\nTransmission occurs through the bite of an infected mosquito.\u00a0Human are the main host and the primary source for the female mosquitoes.
\nThe mosquito becomes infected when it bites a person with dengue virus in their blood. It can\u2019t be spread directly from one person to another person.<\/p>\n

Symptoms
\n<\/strong>Symptoms of Dengue fever usually begin 4 to 6 days after infection<\/span> and last for up to 10 days, may include : sudden, high fever, headaches, pain behind the eyes, joint and muscle pain
\nfatigue, nausea, skin rash.
\nSometimes, symptoms are mild and can be mistaken for those of the flu or another viral infection<\/p>\n

Diagnosis<\/strong>
\nwe should consider in a patient who was in an endemic area within 2 weeks before symptoms onset\u00a0;
\nDengue can be diagnosed by isolation of the virus<\/a>, by serological tests, or by molecular methods.<\/p>\n

Treatment<\/strong>
\nThere is no specific antiviral agents.<\/p>\n

Other interventions for dengue control?<\/h2>\n

Vector control has been the key strategy to control or prevent the transmission of dengue virus.
\nStrategies include:<\/p>\n

    \n
  • preventing mosquitoes from accessing egg-laying habitats by environmental management and modification;<\/li>\n
  • disposing of solid waste properly and removing artificial man-made habitats;<\/li>\n
  • covering, emptying and cleaning of domestic water storage containers on a weekly basis;<\/li>\n
  • applying appropriate insecticides to water storage outdoor containers;<\/li>\n
  • using of personal household protection such as window screens, long-sleeved clothes, insecticide treated materials, coils and vaporizers;<\/li>\n
  • improving community participation and mobilization for sustained vector control;<\/li>\n
  • applying insecticides as space spraying during outbreaks as one of the emergency vector-control measures<\/li>\n<\/ul>\n